EFFICACY OF ADDITIONAL CORTICOSTEROIDS TO MULTIMODAL COCKTAIL PERIARTICULAR INJECTION IN TOTAL KNEE ARTHROPLASTY: A META-ANALYSIS OF RANDOMIZED CONTROLLED TRIALS

Efficacy of additional corticosteroids to multimodal cocktail periarticular injection in total knee arthroplasty: a meta-analysis of randomized controlled trials

Abstract Background As the ultimate method for the treatment of osteoarthritis, total knee arthroplasty (TKA) has been widely used in the clinic.Local injection of multimodal cocktails, including corticosteroids, is commonly used for pain management after TKA.This meta-analysis aims to systematically evaluate the effect of periarticular injection o

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Modified Stability of microRNA-Loaded Nanoparticles

microRNAs represent promising drugs to treat and prevent several diseases, such as diabetes mellitus.microRNA delivery brings many obstacles to overcome, and one strategy to bypass them is the manufacturing of self-assembled microRNA protein nanoparticles.In this work, a microRNA was combined with the cell-penetrating peptide protamine, forming so-

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